What it is
Ashwagandha is an Ayurvedic medicinal herb native to India, North Africa, and the Mediterranean. "Ashwagandha" translates as "smell of horse" — a reference both to its equine-like aroma and its traditional reputation for conferring strength and stamina. The root is the primary used plant part for supplement formulations.
Extraction and standardisation
Root extract is standardised to withanolide content — the primary bioactive compound class. KSM-66 grade (Ixoreal Biomed's proprietary extract) standardises to ≥5% withanolides using a root-only, milk-based extraction process. Our standard grade is ≥2.5% withanolides. For buyers wanting the highest-evidenced specification, KSM-66 is the recommended choice.
Clinical evidence
Over 20 double-blind, placebo-controlled RCTs have been published on ashwagandha root extract in humans. The evidence base covers: cortisol reduction, sleep quality improvement, testosterone in men, thyroid function, endurance performance, and muscle strength. The Chandrasekhar et al. (2012) cortisol RCT and Langade et al. (2019) sleep RCT are the most-cited in DTC marketing.